CD22 Antikörper (Elab Fluor®700)

Produktnummer ABIN7566715

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD22 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD22 Antikörper (Elab Fluor®700) (ABIN7566715)

Target: CD22 (CD22 Molecule (CD22))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD22 Antikörper ist konjugiert mit Elab Fluor®700

Applikation: Flow Cytometry (FACS)

Klon: Cy34-1

Produktdetails anti-CD22 Antikörper (Elab Fluor®700)

Verwendungszweck: Elab Fluor®700 Anti-Mouse CD22 Antibody[Cy34.1]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: E-AB-F09793M1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu CD22

Target: CD22 (CD22 Molecule (CD22))

Andere Bezeichnung: CD22

Hintergrund: Siglec2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,CD22,Cd22,Lyb-8,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig μ chain are augmented in the presence of Cy34.1 mAb.

Gen-ID: 12483

UniProt: P35329