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CD72 Antikörper (FITC)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD72 in FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7566559

Kurzübersicht für CD72 Antikörper (FITC) (ABIN7566559)

Target

Alle CD72 Antikörper anzeigen
CD72 (CD72 Molecule (CD72))

Reaktivität

  • 65
  • 13
  • 3
Human

Wirt

  • 42
  • 36
  • 2
  • 1
Maus

Klonalität

  • 43
  • 34
  • 2
Monoklonal

Konjugat

  • 44
  • 8
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD72 Antikörper ist konjugiert mit FITC

Applikation

  • 36
  • 33
  • 26
  • 22
  • 16
  • 13
  • 10
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

3F3
  • Verwendungszweck

    FITC Anti-Human CD72 Antibody[3F3]

    Isotyp

    IgG2b, kappa
  • Applikationshinweise

    Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
    FCM: 5 µL/test

    Kommentare

    Matching Isotype Control: (ABIN7469794)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    Lagerung

    4 °C

    Informationen zur Lagerung

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    Haltbarkeit

    12 months
  • Target

    CD72 (CD72 Molecule (CD72))

    Andere Bezeichnung

    CD72

    Hintergrund

    Lyb-2,Ly-19.2,Ly-32.2,CD72 is a 39-43 kD type II membrane glycoprotein. It is a disulfide-linked homodimer belonging to C-type lectin family. CD72 is a pan-B cell marker expressed on pre-pre-B cells throughout B cell differentiation with the exception of plasma cells. It is also expressed on follicular dendritic cells, splenic red pulp macrophages (but not on peripheral blood monocytes), and liver Kupffer cells. CD72, a negative coreceptor of B cells, contains immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domain which has been shown to recruit the tyrosine phosphatase SHP-1. Ligation of CD72 with its ligand regulates CD72 tyrosine dephosphorylation and SHP-1 dissociation to promote B cell activation and proliferation. CD100 and CD5 have been shown to be CD72 ligands. The CD100-CD72 interaction plays a role in maintenance of B cell homeostasis.

    Gen-ID

    971

    UniProt

    P21854

    Pathways

    BCR Signaling
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