CD46 Antikörper (APC)

Produktnummer ABIN7566533

Der Maus Monoklonal Anti-CD46-Antikörper wurde für FACS validiert. Er ist geeignet, CD46 in Proben von Human zu detektieren.

Kurzübersicht für CD46 Antikörper (APC) (ABIN7566533)

Target: CD46

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: TRA-2-10

Produktdetails anti-CD46 Antikörper (APC)

Verwendungszweck: APC Anti-Human CD46 Antibody[TRA-2-10]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Kommentare:

Matching Isotype Control: (ABIN7469762)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund: Complementmembranecofactorprotein,measlesvirusreceptor,MCP,CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.

Gen-ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization