NGFB Antikörper (AA 151-220)

Produktnummer ABIN724430

Der Kaninchen Polyklonal Anti-NGFB-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, NGFB in Proben von Human, Ratte, Maus und Hund zu detektieren. Es sind 6+ Publikationen verfügbar.

Kurzübersicht für NGFB Antikörper (AA 151-220) (ABIN724430)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NGFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NGFB Antikörper

Bindungsspezifität: AA 151-220

Kreuzreaktivität: Hund, Human, Maus, Ratte

Homologie: Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NGF beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NGFB Antikörper (ABIN724430)

Shu, Huang, Zeng, He, Luo, Liu, Li, Xu: "Connexin 43 is involved in the sympathetic atrial fibrillation in canine and canine atrial myocytes." in: Anatolian journal of cardiology, Vol. 18, Issue 1, pp. 3-9, (2019) (PubMed).

Lu, Sun, Zhou, Zhang, Ma, Tang: "Effect of Low-level Vagus Nerve Stimulation on Cardiac Remodeling in a Rapid Atrial Pacing-induced Canine Model of Atrial Fibrillation." in: Journal of cardiovascular pharmacology, Vol. 67, Issue 3, pp. 218-24, (2016) (PubMed).

Zhang, Zhang, Liang, Wang, Zheng, Wang: "Choline supplementation alleviates fluoride-induced testicular toxicity by restoring the NGF and MEK expression in mice." in: Toxicology and applied pharmacology, Vol. 310, pp. 205-214, (2016) (PubMed).

Li, Gao, Ma, Jiang, Miao, Jiang, Fan, Wang, Wu, Liu, Wang, Lui, Yuan: "Therapeutic potential of in utero mesenchymal stem cell (MSCs) transplantation in rat foetuses with spina bifida aperta." in: Journal of cellular and molecular medicine, Vol. 16, Issue 7, pp. 1606-17, (2012) (PubMed).

Li, Shen, Di, Li, Geng, Lu, He: "Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma." in: Acta oto-laryngologica, Vol. 132, Issue 3, pp. 314-24, (2012) (PubMed).

Details zu NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Andere Bezeichnung: NGF beta

Hintergrund:

Synonyms: NGFB, HSAN5, Beta-NGF, Beta-nerve growth factor, NGF

Background: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

Gen-ID: 4803

UniProt: P01138

Pathways: NF-kappaB Signalweg, RTK Signalweg, Regulation of Cell Size