Rekombinanter beta Catenin Antikörper
Kurzübersicht für Rekombinanter beta Catenin Antikörper (ABIN7543331)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-B-catenin [3B1D11A8], Mouse IgG1, kappa
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Spezifität
- This antibody binds human beta-catenin. The human β-catenin acts as a multi-functional protein that plays a very important role in cell adhesion and Wnt signaling pathway mediated gene expression regulation. Β-catenin on the cell membrane can be combined with the cytoplasmic domain of E-Cadherin (E-CAD) to form an e-cadherin / β-catenin complex, which mediates mutual adhesion between the same type. It acts as a key regulatory molecule in the Wnt signaling pathway and plays an important role in the occurrence / evolution of the embryonic development and tumor.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing BALB/c mice with human beta-catenin-KLH conjugate in Freund's non-complete adjuvant.
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Isotyp
- IgG1 kappa
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anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Schwein WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf, Affe, Hamster, Avian, Cat, Esel, Ziege, Meerschweinchen, Pferd WB, IF Wirt: Ziege Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reaktivität: Human, Zebrafisch (Danio rerio) WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IF, IHC (p) Wirt: Maus Monoclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, ICC, IP Wirt: Maus Monoclonal C11 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Hamster WB, ICC, IP, ICFC Wirt: Maus Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 4A3H3 unconjugated
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Applikationshinweise
- The binding characterization of this antibody was done using ELISA. The original mouse IgG1 antibody binds human B-catenin with an affinity constant of 4.96 X 10^(9) M^(-1). This antibody was also used in the immunohistochemical analysis of colorectal carcinoma and pancreatic cancer tissues. The immunohistochemical staining pattern of this antibody is similar to commercially available antibody CAT-5H10 (CN112457400).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- B-catenin
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Hintergrund
- CTNNB1, CTNNB, Catenin beta-1, Beta-catenin, CAT-5H10, CGMCC No. 19685
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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