Rekombinanter MSH6 Antikörper
Kurzübersicht für Rekombinanter MSH6 Antikörper (ABIN7543329)
Target
Alle MSH6 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-MSH6 [ABM58060-20A2-PU], Rabbit IgG, kappa
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Spezifität
- This antibody binds human DNA mismatch repair protein MSH6. MSH6 forms a heterodimer with MSH2 to make the human MutSα mismatch repair complex and initiates DNA repair. The DNA mismatch repair system (MMR) is composed of enzyme molecules that specifically repair DNA base mismatches. Defects in expression of MSH6 are often associated with hereditary non-polypatopathic colorectal cancer (HNPCC).
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing BALB/c mice with recombinant human MSH6 protein.
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Isotyp
- IgG kappa
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anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, ELISA, IF, Coat, StM Wirt: Maus Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) antibodyMSH6 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5B11 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 225-333) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 44-MSH6 unconjugated
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Applikationshinweise
- The binding specificity of this antibody for human MSH6 was determined using ELISA. This antibody was capable of detecting recombinant MSH6 in a western blot. This antibody was also used in the immunohistochemical analysis of colon cancer, bladder cancer and testicular tissues. This antibody shows similar staining of MSH6 protein compared to the commercially available antibody 44 (CN111454365).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Andere Bezeichnung
- MSH6
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Hintergrund
- HMSH6, p160, GTBP, GTMBP, DNA mismatch repair protein Msh6, G/T mismatch-binding protein, MutS protein homolog 6, MutS-alpha 160 kDa subunitC, GMCC NO.17492, 44
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UniProt
- P52701
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Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
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