Rekombinanter DLL4 Antikörper

Produktnummer ABIN7543202

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch DLL4 in ELISA, IHC, IF und BP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter DLL4 Antikörper (ABIN7543202)

Target: DLL4 (delta-Like 4 (DLL4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser DLL4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Peptide (BP)

Klon: 61B

Produktdetails anti-DLL4 Antikörper

Verwendungszweck: Anti-DLL4 [61B], Rabbit IgG, kappa

Spezifität: This antibody is specific for the EGF-like 3 domain of Dll4.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with soluble human Dll4-His protein.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: DLL4

Hintergrund: Delta-like protein 4, Drosophila Delta homolog 4, Delta4

UniProt: Q9NR61

Pathways: Notch Signalweg