Rekombinanter DLL4 Antikörper
Kurzübersicht für Rekombinanter DLL4 Antikörper (ABIN7543201)
Target
Alle DLL4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-DLL4 [61B], Mouse IgG2a, kappa
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Spezifität
- This antibody is specific for the EGF-like 3 domain of Dll4.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing mice with soluble human Dll4-His protein.
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Isotyp
- IgG2a kappa
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Applikationshinweise
- U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- DLL4 (delta-Like 4 (DLL4))
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Andere Bezeichnung
- DLL4
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Hintergrund
- Delta-like protein 4, Drosophila Delta homolog 4, Delta4
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UniProt
- Q9NR61
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Pathways
- Notch Signalweg
Target
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