Rekombinanter beta Catenin Antikörper

Produktnummer ABIN7543130

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch beta Catenin in WB, IHC, FACS, IF und EMSA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter beta Catenin Antikörper (ABIN7543130)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser beta Catenin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Electrophoretic Mobility-Shift Assay (EMSA)

Klon: 15B8

Produktdetails anti-beta Catenin Antikörper

Verwendungszweck: Anti-beta catenin [15B8], Rabbit IgG, kappa

Spezifität: This antibody recognizes beta catenin. It does not react with plakoglobin. β-Catenin plays a dual function in the cell including cell-cell adhesion and as a component of the Wnt (wingless) signaling pathway.

Kreuzreaktivität: Huhn, Rind (Kuh), Hund, Maus, Ratte

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with a recombinant full length beta-catenin of chicken origin.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody is recommended for the detection and analysis of beta-catenin via various methods, such as Western blot, flow cytometry and immunofluorescence of cells and tissues. For instance, the antibody 15B8 was utilized in labelling beta-catenin in oral mucosa samples via immunohistochemistry (Das et al., 2013). Another group used this antibody in the identification of beta-catenin in extracts from K562 cells via Western blots (Kotula et al., 2014). Furthermore, this antibody was applied during immunohistochemistry stainings of transverse sections taken through the midbrain region of 8-9ss embryos (Schiffmacher et al., 2016). Finally,beta-catenin is a very popular marker used to outline the cell membrane, this antibody might be utilized for such purposes (Zhang et al., 2017).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung: beta catenin

Hintergrund: Catenin beta-1, Beta-catenin, β-catenin, β catenin

UniProt: P35222

Pathways: Peptide Hormone Metabolism