Rekombinanter beta Catenin Antikörper

Produktnummer ABIN7543129

Der Maus Monoklonal anti-beta Catenin Antikörper (Klon 15B8) (ABIN7543129) detektiert spezifisch beta Catenin in WB, IHC, IF, FACS und EMSA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Huhn und Hund.

Kurzübersicht für Rekombinanter beta Catenin Antikörper (ABIN7543129)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta Catenin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Electrophoretic Mobility-Shift Assay (EMSA)

Klon: 15B8

Produktdetails anti-beta Catenin Antikörper

Verwendungszweck: Anti-beta catenin [15B8], Mouse IgG1, kappa

Spezifität:

This antibody recognizes beta catenin. It does not react with plakoglobin. β-Catenin plays a dual function in the cell including cell-cell adhesion and as a component of the Wnt (wingless) signaling pathway.

Application Notes original Clone: This antibody is recommended for the detection and analysis of beta-catenin via various methods, such as Western blot, flow cytometry and immunofluorescence of cells and tissues. For instance, the antibody 15B8 was utilized in labelling beta-catenin in oral mucosa samples via immunohistochemistry (Das et al., 2013). Another group used this antibody in the identification of beta-catenin in extracts from K562 cells via Western blots (Kotula et al., 2014). Furthermore, this antibody was applied during immunohistochemistry stainings of transverse sections taken through the midbrain region of 8-9ss embryos (Schiffmacher et al., 2016). Finally,beta-catenin is a very popular marker used to outline the cell membrane, this antibody might be utilized for such purposes (Zhang et al., 2017).

Kreuzreaktivität: Huhn, Rind (Kuh), Hund, Maus, Ratte

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with a recombinant full length beta-catenin of chicken origin.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung: beta catenin

Hintergrund: Catenin beta-1, Beta-catenin, β-catenin, β catenin

UniProt: P35222

Pathways: Peptide Hormone Metabolism