NGFR Antikörper (FITC)

Produktnummer ABIN7540431

Der Maus Monoklonal Anti-NGFR-Antikörper wurde für FACS und ICFC validiert. Er ist geeignet, NGFR in Proben von Human, Non-Human Primate, Kaninchen, Cat und Frettchen zu detektieren.

Kurzübersicht für NGFR Antikörper (FITC) (ABIN7540431)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität: Human, Non-Human Primate, Kaninchen, Cat, Frettchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NGFR Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: NGFR5

Produktdetails anti-NGFR Antikörper (FITC)

Verwendungszweck: Anti-Hu CD271 FITC

Spezifität: The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Keine Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Purified CD271 protein isolated from human melanoma cell line A875

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Andere Bezeichnung: CD271

Hintergrund:

NCBI Full Gene Name: nerve growth factor receptor

Description: CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Other names: TNFRSF16, NGFR, p75NTR, p75NGFR

Gene name: NGFR

Gen-ID: 4804

UniProt: P08138

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding