Galectin 3 Antikörper (PE)

Produktnummer ABIN7540408

Dieses Anti-Galectin 3-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Galectin 3 in FACS und ICFC. Geeignet für Human und Maus.

Kurzübersicht für Galectin 3 Antikörper (PE) (ABIN7540408)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Galectin 3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: M3-38

Produktdetails anti-Galectin 3 Antikörper (PE)

Verwendungszweck: Anti-Galectin-3 PE

Spezifität: The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: murine galectin-3

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3

Hintergrund:

NCBI Full Gene Name: lectin, galactose binding, soluble 3

Description: Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.

Other names: Mac-2, GBP, Gal-3, L-34

Gene name: Lgals3

Gen-ID: 16854

UniProt: P16110

Pathways: RTK Signalweg