APC Antikörper (AA 2644-2843)
Kurzübersicht für APC Antikörper (AA 2644-2843) (ABIN7539857)
Target
Alle APC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2644-2843
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Verwendungszweck
- APC Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human APC (AA: 2644-2843) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- APC (Adenomatous Polyposis Coli (APC))
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Andere Bezeichnung
- APC
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Hintergrund
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
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Molekulargewicht
- 311.6 kDa
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Gen-ID
- 324
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UniProt
- P25054
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Pathways
- WNT Signalweg, Stem Cell Maintenance, Cell-Cell Junction Organization
Target
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