APC Antikörper

Produktnummer ABIN7265452

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch APC in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APC Antikörper (ABIN7265452)

Target: APC (Adenomatous Polyposis Coli (APC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser APC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-APC Antikörper

Verwendungszweck: APC Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human APC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu APC

Target: APC (Adenomatous Polyposis Coli (APC))

Andere Bezeichnung: APC

Hintergrund: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008],APC,BTPS2,DP2,DP2.5,DP3,GS,PPP1R46,Apoptosis,Cancer,Cardiovascular,Cell Adhesion,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cell Type Marker,Cell Type Marker_Oligodendrocyte marker,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ESC Pluripotency and Differentiation,Heart,Heart_Cardiogenesis,Neuroscience,Signal Transduction,Stem Cells,Transcription Factors,Tumor suppressors,Wnt/β-Catenin Signaling Pathway,APC

Molekulargewicht: 160kDa

Gen-ID: 324

UniProt: P25054

Pathways: WNT Signalweg, Stem Cell Maintenance, Cell-Cell Junction Organization