GAB2 Antikörper (AA 332-476)
Kurzübersicht für GAB2 Antikörper (AA 332-476) (ABIN7539834)
Target
Alle GAB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 332-476
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Verwendungszweck
- GAB2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human GAB2 (AA: 332-476) expressed in E. Coli.
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Isotyp
- IgG2a
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anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr452) antibody
GAB2 Reaktivität: Human, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer159) antibodyGAB2 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 273-484) antibodyGAB2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 3-30), (N-Term) antibodyGAB2 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB21209 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser159) antibodyGAB2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 357-607) antibodyGAB2 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 601-676) antibodyGAB2 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer623) antibodyGAB2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr643) antibodyGAB2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (C-Term) antibodyGAB2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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Andere Bezeichnung
- GAB2
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Hintergrund
- This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
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Molekulargewicht
- 74.5 kDa
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Gen-ID
- 9846
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UniProt
- Q9UQC2
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effekt
Target
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