Mre11 Antikörper (AA 182-582)

Produktnummer ABIN7539820

Der Maus Monoklonal Anti-Mre11-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, Mre11 in Proben von Human, Ratte, Maus und Affe zu detektieren.

Kurzübersicht für Mre11 Antikörper (AA 182-582) (ABIN7539820)

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mre11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 7C8A9

Produktdetails anti-Mre11 Antikörper

Bindungsspezifität: AA 182-582

Verwendungszweck: MRE11 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MRE11 (AA: 182-582) expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Andere Bezeichnung: MRE11

Hintergrund: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Molekulargewicht: 80.6 kDa

Gen-ID: 4361

UniProt: P49959

Pathways: DNA Reparatur