IRF3 Antikörper (AA 1-150)
Kurzübersicht für IRF3 Antikörper (AA 1-150) (ABIN7539801)
Target
Alle IRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-150
-
Verwendungszweck
- IRF3 Antibody
-
Aufreinigung
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.
-
Isotyp
- IgG2b
-
-
-
-
Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
Andere Bezeichnung
- IRF3
-
Hintergrund
-
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.
-
Molekulargewicht
- 47.2 kDa
-
Gen-ID
- 3661
-
UniProt
- Q14653
-
Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Target
-