TCF7 Antikörper (AA 168-358)

Produktnummer ABIN7539769

Der Maus Monoklonal Anti-TCF7-Antikörper wurde für ELISA, IHC, ICC und FACS validiert. Er ist geeignet, TCF7 in Proben von Human zu detektieren.

Kurzübersicht für TCF7 Antikörper (AA 168-358) (ABIN7539769)

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCF7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 1B4E9

Produktdetails anti-TCF7 Antikörper

Bindungsspezifität: AA 168-358

Verwendungszweck: TCF7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human TCF7 (AA: 168-358) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu TCF7

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Andere Bezeichnung: TCF7

Hintergrund: This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

Molekulargewicht: 41.6 kDa

Gen-ID: 6932

UniProt: P36402

Pathways: WNT Signalweg