Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TCF7 Antikörper

TCF7 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7075952
  • Target Alle TCF7 Antikörper anzeigen
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Reaktivität
    • 56
    • 39
    • 17
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 51
    • 5
    • 2
    Kaninchen
    Klonalität
    • 51
    • 7
    Polyklonal
    Konjugat
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser TCF7 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 18
    • 14
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse TCF7
  • Applikationshinweise
    IHC/IF (M,R) 1:600-1:1200/1:600-1:1200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Andere Bezeichnung
    TCF7 (TCF7 Produkte)
    Synonyme
    TCF-1 antikoerper, AI465550 antikoerper, Tcf1 antikoerper, Xtcf-1 antikoerper, Xtcf1 antikoerper, tcf-1 antikoerper, tcf1 antikoerper, tcf7 antikoerper, transcription factor 7 antikoerper, transcription factor 7, T cell specific antikoerper, transcription factor 7 S homeolog antikoerper, TCF7 antikoerper, Tcf7 antikoerper, tcf7 antikoerper, tcf7.S antikoerper
    Hintergrund
    TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
    Gen-ID
    21414
    NCBI Accession
    NP_001300910
    UniProt
    Q00417
    Pathways
    WNT Signalweg
Sie sind hier: