TCF7 Antikörper (N-Term)

Produktnummer ABIN6972847

Produktdetails anti-TCF7 Antikörper

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: TCF7 (Transcription Factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1. TCF7 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of human TCF7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu TCF7

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Andere Bezeichnung: TCF7 (TCF7 Produkte)

Synonyme: TCF-1 antikoerper, AI465550 antikoerper, Tcf1 antikoerper, Xtcf-1 antikoerper, Xtcf1 antikoerper, tcf-1 antikoerper, tcf1 antikoerper, tcf7 antikoerper, transcription factor 7 antikoerper, transcription factor 7, T cell specific antikoerper, transcription factor 7 S homeolog antikoerper, TCF7 antikoerper, Tcf7 antikoerper, tcf7 antikoerper, tcf7.S antikoerper

Molekulargewicht: 52 & 55 kDa

NCBI Accession: NP_003193

Pathways: WNT Signalweg