CD40 Ligand Antikörper

Produktnummer ABIN7539620

Der Maus Monoklonal anti-CD40 Ligand Antikörper (Klon 24-31) (ABIN7539620) detektiert spezifisch CD40 Ligand in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD40 Ligand Antikörper (ABIN7539620)

Target: CD40 Ligand (CD40LG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 24-31

Produktdetails anti-CD40 Ligand Antikörper

Verwendungszweck: AF/LE Purified Anti-Human CD154 Antibody [24-31]

Spezifität: Human

Aufreinigung: Protein A/G Purified

Endotoxin-Niveau: Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

Immunogen: Recombinant Human CD154 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FCM:2 μg/mL(1x10^5-5x10^5 cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS.

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154

Hintergrund: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Gen-ID: 959

UniProt: P29965

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints