IL3RA Antikörper

Produktnummer ABIN7539423

Der Maus Monoklonal anti-IL3RA Antikörper (Klon HI12H7) (ABIN7539423) detektiert spezifisch IL3RA in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL3RA Antikörper (ABIN7539423)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: HI12H7

Produktdetails anti-IL3RA Antikörper

Verwendungszweck: CD123 Unconjugated Antibody

Produktmerkmale: The clone HI12H7, a mouse monoclonal antibody, specifically targets the 70 kDa transmembrane α chain of the IL3 receptor, also known as CD123. This receptor is prominently expressed in various cells within the hematopoietic system, including hematopoietic progenitor cells, monocytes, and B-lymphocytes. CD123 plays a crucial role in regulating the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Notably, elevated levels of CD123 expression are frequently observed in a range of hematolymphoid neoplasms. These include acute myeloid leukemia, blastic plasmacytoid dendritic cell neoplasm, acute lymphoblastic leukemia, hairy cell leukemia, systemic mastocytosis, and certain types of B cells.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human IL3Ralpha transfected COS cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: CD123

Gen-ID: 3815

NCBI Accession: NP_000213, NP_001087241

UniProt: P10721

Pathways: JAK-STAT Signalweg