FGFR3 Antikörper
Kurzübersicht für FGFR3 Antikörper (ABIN7539297)
Target
Alle FGFR3 Antikörper anzeigenFragment
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- FGFR-3 neutralizing antibody antibody
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Spezifität
- Chromosomal location:4p16.3
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Aufreinigung
- Ion exchange chromatography
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.
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Haltbarkeit
- 24 months
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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Andere Bezeichnung
- FGFR-3
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Hintergrund
- FGFR3, ACH, CEK2, JTK4, CD333, HSFGFR3EX,Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
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Gen-ID
- 2261
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NCBI Accession
- NM_000142, NP_000133
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UniProt
- P22607
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Growth Factor Binding
Target
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