Der Kaninchen Polyklonal Anti-Prostate Specific Antigen-Antikörper wurde für ELISA und WB validiert. Er ist geeignet, Prostate Specific Antigen in Proben von Human zu detektieren.
PSA
Reaktivität: Human
IHC (p)
Wirt: Kaninchen
Monoclonal
L15-V
unconjugated
Applikationshinweise
Western blot: 1.0 -5.0 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Glycine pH 7.2
Lagerung
4 °C,-80 °C
Informationen zur Lagerung
Short term up to 1 month at 2-8°C, long term can be held for up to five years at -70°C
Target
Prostate Specific Antigen (PSA)
Andere Bezeichnung
PSA
Hintergrund
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms