Der Kaninchen-Polyklonal Anti-Prostate Specific Antigen-Antikörper wurde für ELISA und WB validiert. Er ist geeignet zum Nachweis von Prostate Specific Antigen in Proben aus Human.
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Short term up to 1 month at 2-8°C, long term can be held for up to five years at -70°C
Target
Prostate Specific Antigen (PSA)
Andere Bezeichnung
PSA
Hintergrund
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms