ITGAL
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
MEM-25
PE
Applikationshinweise
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
Lagerung
4 °C
Informationen zur Lagerung
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Haltbarkeit
12 months
Target
ITGAL
(Integrin alpha-L (ITGAL))
Andere Bezeichnung
CD11a
Hintergrund
CD11a,Integrin alpha-L,Itgal,CD11 antigen-like family member A,LFA-1A,Lymphocyte antigen 15,Ly-15,CD11a,CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).