Cyclin D1 Antikörper
Kurzübersicht für Cyclin D1 Antikörper (ABIN7529091)
Target
Alle Cyclin D1 (CCND1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
 - Cyclin D1 Unconjugated Antibody
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Produktmerkmale
 - The clone C-D1A5, a mouse monoclonal antibody selectively binds to ~34 kD protein is encoded by the CCND1 gene known as Cyclin D1. It is expressed in all adult human tissues except for cells derived from bone marrow stem cell lines (both lymphoid and myeloid), Cyclin D1 is an important regulator of cell cycle progression and can function as a transcriptional co-regulator. The overexpression of cyclin D1 has been linked to the development and progression of cancer cells.
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Aufreinigung
 - Purified
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Reinheit
 - >95 %
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Immunogen
 - Human full length recombinant cyclin D1 protein
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Isotyp
 - IgG2a, kappa
 
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Applikationshinweise
 - Optimal working dilution should be determined by the investigator.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Buffer
 - PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
 
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- Cyclin D1 (CCND1)
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Andere Bezeichnung
 - Cyclin D1
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Gen-ID
 - 5788
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NCBI Accession
 - NM_002838
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UniProt
 - P08575
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Pathways
 - PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
 
Target
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