Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Perforin 1 Antikörper (APC)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Perforin 1 in ICFC. Er zeigt eine Reaktivität gegenüber Human und Rind (Kuh).
Produktnummer ABIN7506003

Kurzübersicht für Perforin 1 Antikörper (APC) (ABIN7506003)

Target

Alle Perforin 1 (PRF1) Antikörper anzeigen
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reaktivität

  • 92
  • 29
  • 8
  • 8
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
Human, Rind (Kuh)

Wirt

  • 65
  • 51
  • 3
Maus

Klonalität

  • 66
  • 53
Monoklonal

Konjugat

  • 66
  • 15
  • 14
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Perforin 1 Antikörper ist konjugiert mit APC

Applikation

  • 59
  • 47
  • 39
  • 24
  • 23
  • 23
  • 10
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Intracellular Flow Cytometry (ICFC)

Klon

DG9
  • Verwendungszweck

    Anti-Perforin APC

    Spezifität

    The mouse monoclonal antibody dG9 (also known as deltaG9) recognizes perforin, a 70 kDa protein expressed in cytoplasmic granules of cytotoxic T cells and NK cells.

    Keine Kreuzreaktivität

    Maus

    Aufreinigung

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    purified granules from human YT lymphoma cell line

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    Andere Bezeichnung

    Perforin

    Hintergrund

    Perforin 1,Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.,PRF1, P1, PFP, HPLH2

    Gen-ID

    5551

    UniProt

    P14222

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose
Sie sind hier:
Chat with us!