Galectin 3 Antikörper

Produktnummer ABIN7505976

Dieser Ratte Monoklonal Antikörper detektiert spezifisch Galectin 3 in WB, ICC, IP, IHC (p), FACS und ICFC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Galectin 3 Antikörper (ABIN7505976)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: M3-38

Produktdetails anti-Galectin 3 Antikörper

Verwendungszweck: Anti-Galectin-3 Purified

Produktmerkmale: The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.

Aufreinigung: Purified by protein-G affinity chromatography.

Immunogen: murine galectin-3

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 2-6 μg/mL. Extracellular and intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3

Hintergrund: Lectin, galactose binding, soluble 3,Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.,Mac-2, GBP, Gal-3, L-34

Gen-ID: 16854

UniProt: P16110

Pathways: RTK Signalweg