DLL4 Antikörper (APC)
Kurzübersicht für DLL4 Antikörper (APC) (ABIN7505974)
Target
Alle DLL4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-DLL4 APC
-
Produktmerkmale
- The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
-
Aufreinigung
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
-
Immunogen
- recombinant soluble human DLL4
-
Isotyp
- IgG1, kappa
-
-
-
-
Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.1 mg/mL
-
Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Do not freeze,Protect from prolonged exposure to light
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
- DLL4 (delta-Like 4 (DLL4))
-
Andere Bezeichnung
- DLL4
-
Hintergrund
- Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
-
Gen-ID
- 54567
-
UniProt
- Q9NR61
-
Pathways
- Notch Signalweg
Target
-