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DLL4 Antikörper (APC)

Der Maus Monoklonal Anti-DLL4-Antikörper wurde für FACS validiert. Er ist geeignet, DLL4 in Proben von Human zu detektieren.
Produktnummer ABIN7505974

Kurzübersicht für DLL4 Antikörper (APC) (ABIN7505974)

Target

Alle DLL4 Antikörper anzeigen
DLL4 (delta-Like 4 (DLL4))

Reaktivität

  • 59
  • 42
  • 19
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 64
  • 18
  • 9
  • 5
  • 1
Maus

Klonalität

  • 65
  • 31
  • 1
Monoklonal

Konjugat

  • 60
  • 9
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DLL4 Antikörper ist konjugiert mit APC

Applikation

  • 50
  • 34
  • 23
  • 15
  • 13
  • 13
  • 11
  • 10
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

MHD4-46
  • Verwendungszweck

    Anti-DLL4 APC

    Spezifität

    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

    Aufreinigung

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    recombinant soluble human DLL4

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.1 mg/mL

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    DLL4 (delta-Like 4 (DLL4))

    Andere Bezeichnung

    DLL4

    Hintergrund

    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4

    Gen-ID

    54567

    UniProt

    Q9NR61

    Pathways

    Notch Signalweg
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