CD79a Antikörper
Kurzübersicht für CD79a Antikörper (ABIN7505955)
Target
Alle CD79a (CD79A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD79a Purified
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Produktmerkmale
- The mouse monoclonal antibody ZL7.4 interacts with extracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- IgM complex isolated from Daudi cells
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Isotyp
- IgG1, kappa
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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 176-226) antibody
CD79A Reaktivität: Human, Maus FACS, WB, IHC, IP, ICC Wirt: Kaninchen Monoclonal BLR234K unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Affe FACS, IF, WB, IHC Wirt: Maus Monoclonal JCB117-HM47-A9 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Affe, Hund FACS, IF, WB, IHC Wirt: Kaninchen Monoclonal IGA-1790R unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-145) antibodyCD79A Reaktivität: Human IF, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 30-193) antibodyCD79A Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A Reaktivität: Human FACS, IF, IHC Wirt: Maus Monoclonal rIGA-764 unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (FITC)CD79A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Huhn, Kaninchen, Pferd, Meerschweinchen, Opossum ICFC Wirt: Maus Monoclonal HM57 FITC
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-143) antibodyCD79A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Monoclonal BLR232K unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222), (C-Term) antibodyCD79A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Huhn, Kaninchen, Pferd, Meerschweinchen, Hund, Non-Human Primate FACS, WB, IHC (p), IP Wirt: Maus Monoclonal HM47 unconjugated
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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Andere Bezeichnung
- CD79a
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Hintergrund
- CD79a molecule,CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.,BCR alpha, Ig-alpha, MB-1, IGA
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Gen-ID
- 973
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UniProt
- P11912
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Pathways
- BCR Signaling
Target
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