IL2RG Antikörper (APC)

Produktnummer ABIN7505854

Der Ratte Monoklonal Anti-IL2RG-Antikörper wurde für FACS validiert. Er ist geeignet, IL2RG in Proben von Human und Hund zu detektieren.

Kurzübersicht für IL2RG Antikörper (APC) (ABIN7505854)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Human, Hund

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2RG Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: TUGh4

Produktdetails anti-IL2RG Antikörper (APC)

Verwendungszweck: Anti-Hu CD132 APC

Spezifität: The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human CD132-transfected cell line

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: CD132

Hintergrund: Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

Gen-ID: 3561

UniProt: P31785

Pathways: JAK-STAT Signalweg, Growth Factor Binding