Integrin Alpha2b Antikörper (PE-CF®594)
Kurzübersicht für Integrin Alpha2b Antikörper (PE-CF®594) (ABIN7489295)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD41a PE-CF594 Antibody
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Produktmerkmale
- The clone 962C1, a mouse monoclonal antibody, reacts with the human CD41 Molecule, the integrin alpha-IIb also known as platelet GPIIb. CD41 is composed of two subunits GPIIbα (120 kDa) and GPIIbβ (23 kDa) that interact with CD61 to form a functional protein receptor in the presence of calcium. This protein receptor involves in the blood coagulation system, by mediating platelet adhesion and aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins like von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocytes and platelets. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Recombinant full-length human Integrin alpha IIb protein
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Isotyp
- IgG1, kappa
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Applikationshinweise
- We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
- CD41a
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Gen-ID
- 3674
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UniProt
- P08514
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Pathways
- Integrin Complex
Target
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