Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper (ABIN7487736)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Anti-Integrin alpha 4 [Natalizumab], Mouse IgG1, kappa
-
Spezifität
- This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
-
Produktmerkmale
-
Original Species of Ab: Human
Original Format of Ab: IgG4
-
Aufreinigung
- Protein A affinity purified
-
Immunogen
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
- This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
-
Kommentare
-
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- ITGA4 (Natalizumab Biosimilar)
-
Hintergrund
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
-
UniProt
- P13612
Target
-