Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper (ABIN5668197)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Anti-Integrin alpha 4 [Natalizumab], Rabbit IgG, kappa
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Spezifität
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This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
Application Notes original Clone: This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
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Produktmerkmale
- NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
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Aufreinigung
- Protein A affinity purified
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Reinheit
- > 98 % as determined by SDS-PAGE
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Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
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Immunogen
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
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Isotyp
- IgG, kappa
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anti-ITGA4 (Natalizumab Biosimilar) antibody
Research Grade Reaktivität: Human FACS Wirt: Humanized Monoclonal unconjugated Recombinant Antibody
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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OriginalSpeciesName: Human
OriginalFormat: IgG4
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ITGA4 (Natalizumab Biosimilar)
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Hintergrund
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
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UniProt
- P13612
Target
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