Rekombinanter ITGA4 (Natalizumab Biosimilar) Antikörper
Reaktivität: Human
FACS, BR
Wirt: Human
Monoclonal
unconjugated
Recombinant Antibody
(1 reference)-
- Target Alle ITGA4 (Natalizumab Biosimilar) Produkte
- ITGA4 (Natalizumab Biosimilar)
- Antikörpertyp
- Recombinant Antibody
- Reaktivität
- Human
-
Wirt
-
Human
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser ITGA4 (Natalizumab Biosimilar) Antikörper ist unkonjugiert
- Applikation
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Spezifität
- This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
- Produktmerkmale
-
OriginalSpeciesName: Human
OriginalFormat: IgG4
- Aufreinigung
- Purified antibody.
- Reinheit
- > 98 % as determined by SDS-PAGE
- Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
- Isotyp
- IgG4 kappa
-
anti-ITGA4 (Natalizumab Biosimilar) antibody
Reaktivität: Human FACS, BR Wirt: Kaninchen Chimeric unconjugated Recombinant Antibody
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- Applikationshinweise
- This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
- Kommentare
-
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." in: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
-
: "An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family." in: PloS one, Vol. 17, Issue 9, pp. e0274667, (2022) (PubMed).
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- Target
- ITGA4 (Natalizumab Biosimilar)
- Abstract
- ITGA4 (Natalizumab Biosimilar) Produkte
- Synonyme
- CD49D antikoerper, IA4 antikoerper, integrin subunit alpha 4 antikoerper, ITGA4 antikoerper
- Hintergrund
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
- UniProt
- P13612
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