ITGAL Antikörper

Produktnummer ABIN7468487

Dieses Anti-ITGAL-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von ITGAL in FACS. Geeignet für Human.

Kurzübersicht für ITGAL Antikörper (ABIN7468487)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: GT0011

Produktdetails anti-ITGAL Antikörper

Kreuzreaktivität: Maus

Aufreinigung: Affinity purified by Protein G.

Immunogen: The immunogen used to generate this antibody corresponds to human CD11a

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: integrin subunit alpha L

Hintergrund:

Synonyms: integrin subunit alpha L , CD11A , LFA-1 , LFA1A

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molekulargewicht: 129 kDa

Gen-ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex