COPS6 Antikörper

Produktnummer ABIN7468168

Der Kaninchen Polyklonal Anti-COPS6-Antikörper wurde für WB validiert. Er ist geeignet, COPS6 in Proben von Human zu detektieren.

Kurzübersicht für COPS6 Antikörper (ABIN7468168)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COPS6 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CSN6. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.88 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Andere Bezeichnung: COP9 signalosome subunit 6

Hintergrund:

Synonyms: COP9 signalosome subunit 6 , CSN6 , MOV34-34KD

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq]

Molekulargewicht: 36 kDa

Gen-ID: 10980

UniProt: Q7L5N1

Pathways: Zellzyklus