COPS6 Antikörper (Middle Region)

Produktnummer ABIN2788037

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch COPS6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für COPS6 Antikörper (Middle Region) (ABIN2788037)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COPS6 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: COPS6 Antibody - middle region

Sequenz: DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COPS6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59350-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-COPS6 Antikörper (ABIN2788037)

Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

Details zu COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Andere Bezeichnung: COPS6

Hintergrund:

Targeted Subunit: 6

Background Information: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Gene Name: COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)

Alternative Symbols: CSN6, MOV34-34KD

Protein Name: COP9 signalosome complex subunit 6

Molekulargewicht: 36kDa

Gen-ID: 10980

NCBI Accession: NP_006824

UniProt: Q7L5N1

Pathways: Zellzyklus