NCOA1 Antikörper (AA 477-947)

Produktnummer ABIN7466744

Dieses Anti-NCOA1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NCOA1 in WB, IP und ChIP. Geeignet für Human.

Kurzübersicht für NCOA1 Antikörper (AA 477-947) (ABIN7466744)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCOA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Klon: 1135

Produktdetails anti-NCOA1 Antikörper

Bindungsspezifität: AA 477-947

Kreuzreaktivität: Human, Affe, Maus, Ratte

Aufreinigung: Protein G purified

Immunogen: Amino acids 477-947 of human SRC-1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IP: 0.5 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Andere Bezeichnung: nuclear receptor coactivator 1

Hintergrund: Nuclear receptor coactivator 1 , F-SRC-1 , KAT13A , RIP160 , SRC1 , bHLHe42 , bHLHe74,The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Molekulargewicht: 157 kDa

Gen-ID: 8648

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha