NLRC4 Antikörper (N-Term)

Produktnummer ABIN7466246

Dieses Anti-NLRC4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NLRC4 in WB. Geeignet für Human.

Kurzübersicht für NLRC4 Antikörper (N-Term) (ABIN7466246)

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NLRC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: GT1387

Produktdetails anti-NLRC4 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human

Aufreinigung: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human CARD12. The exact sequence is proprietary.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human NLRC4-transfected 293T cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Andere Bezeichnung: NLR family CARD domain containing 4

Hintergrund: NLR family CARD domain containing 4 , AIFEC , CARD12 , CLAN , CLAN1 , CLANA , CLANB , CLANC , CLAND , CLR2.1 , FCAS4 , IPAF,This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Molekulargewicht: 116 kDa

Gen-ID: 58484

UniProt: Q9NPP4

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome