Fibulin 5 Antikörper (C-Term)
Kurzübersicht für Fibulin 5 Antikörper (C-Term) (ABIN7465812)
Target
Alle Fibulin 5 (FBLN5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Fibulin 5. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: HeLa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Fibulin 5 (FBLN5)
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Andere Bezeichnung
- fibulin 5
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Hintergrund
- Fibulin 5 , ADCL2 , ARCL1A , ARMD3 , DANCE , EVEC , FIBL-5 , HNARMD , UP50,The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq]
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Molekulargewicht
- 50 kDa
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Gen-ID
- 10516
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UniProt
- Q9UBX5
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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