RNF168 Antikörper

Produktnummer ABIN7464630

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNF168 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RNF168 Antikörper (ABIN7464630)

Target: RNF168 (Ring Finger Protein 168 (RNF168))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF168 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF168 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RNF168. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human RNF168-transfected 293T cells , MDA-MB-231 nuclear extract

Validation: Orthogonal, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RNF168

Target: RNF168 (Ring Finger Protein 168 (RNF168))

Andere Bezeichnung: ring finger protein 168

Hintergrund: Ring finger protein 168 , hRNF168,The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repair proteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSB repair (Stewart et al., 2009 [PubMed 19203578]).[supplied by OMIM]

Molekulargewicht: 65 kDa

Gen-ID: 165918

UniProt: Q8IYW5

Pathways: Production of Molecular Mediator of Immune Response