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ROCK2 Antikörper (pSer1366)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ROCK2 in WB, IF, IHC (p), ICC, IHC (fro) und IA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7464444

Kurzübersicht für ROCK2 Antikörper (pSer1366) (ABIN7464444)

Target

Alle ROCK2 Antikörper anzeigen
ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reaktivität

  • 97
  • 55
  • 54
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 91
  • 8
  • 1
Kaninchen

Klonalität

  • 87
  • 13
Polyklonal

Konjugat

  • 55
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ROCK2 Antikörper ist unkonjugiert

Applikation

  • 82
  • 38
  • 27
  • 27
  • 24
  • 17
  • 17
  • 13
  • 10
  • 8
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)

Güteklasse

KO Validated
  • Bindungsspezifität

    • 15
    • 15
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1366

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide surrounding phospho Ser1366 of human ROCK2. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: HeLa , 293T

    Validation: KO/KD, Orthogonal, Overexpression

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.32 mg/mL

    Buffer

    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

    Andere Bezeichnung

    Rho associated coiled-coil containing protein kinase 2

    Hintergrund

    Rho associated coiled-coil containing protein kinase 2 , ROCK-II,The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq]

    Molekulargewicht

    161 kDa

    Gen-ID

    9475

    UniProt

    O75116

    Pathways

    Microtubule Dynamics, WNT Signalweg, Tube Formation
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