ITGA2 Antikörper (PE-Cy5.5)

Produktnummer ABIN7457415

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch ITGA2 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für ITGA2 Antikörper (PE-Cy5.5) (ABIN7457415)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGA2 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: DX5

Produktdetails anti-ITGA2 Antikörper (PE-Cy5.5)

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: PE/Cyanine5.5 Rat IgM, κ Isotype Control

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: CD49b

Hintergrund: Integrin alpha-2,CD49 antigen-like family member B,Collagen receptor,Platelet membrane glycoprotein Ia,GPIa,VLA-2 subunit alpha,CD49b,DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Gen-ID: 16398

UniProt: Q62469

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex