KIT Antikörper (Biotin)

Produktnummer ABIN7456662

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch KIT in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für KIT Antikörper (Biotin) (ABIN7456662)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser KIT Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 2B8

Produktdetails anti-KIT Antikörper (Biotin)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: Biotin Rat IgG2b, κ Isotype Control (ABIN7469857)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: CD117

Hintergrund: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117,CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Gen-ID: 16590

UniProt: P05532

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity