CD35 Antikörper (Biotin)

Produktnummer ABIN7456648

Der Maus Monoklonal Anti-CD35-Antikörper wurde für FACS validiert. Er ist geeignet, CD35 in Proben von Human zu detektieren.

Kurzübersicht für CD35 Antikörper (Biotin) (ABIN7456648)

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD35 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: E11

Produktdetails anti-CD35 Antikörper (Biotin)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu CD35

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Andere Bezeichnung: CD35

Hintergrund: Complement receptor type 1,CR1,C3b/C4b receptor,CD35,CR1,C3BR,CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Gen-ID: 1378

UniProt: P17927

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity