IL2RG Antikörper (Biotin)

Produktnummer ABIN7456623

Dieser Ratte Monoklonal Antikörper erkennt spezifisch IL2RG in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für IL2RG Antikörper (Biotin) (ABIN7456623)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2RG Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 3E12

Produktdetails anti-IL2RG Antikörper (Biotin)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: Biotin Rat IgG2b, κ Isotype Control (ABIN7469857)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: CD132

Hintergrund: Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132,CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Gen-ID: 16186

UniProt: P34902

Pathways: JAK-STAT Signalweg, Growth Factor Binding