Rekombinanter DDR1 Antikörper

Produktnummer ABIN7490834

Der Human Chimeric anti-DDR1 Antikörper wird verwendet zum Nachweis von DDR1 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Rekombinanter DDR1 Antikörper (ABIN7490834)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Antikörpertyp: Recombinant Antibody

Fragment: Fc fragment

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser DDR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: DMC480

Produktdetails anti-DDR1 Antikörper

Verwendungszweck: Anti-DDR1 antibody(DMC480), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Andere Bezeichnung: DDR1

Hintergrund: CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, MCK-10, HGK2, CD167a,
Description: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

UniProt: Q08345

Pathways: RTK Signalweg, Smooth Muscle Cell Migration