Rekombinanter BMI1 Antikörper (AA 250-300)
Kurzübersicht für Rekombinanter BMI1 Antikörper (AA 250-300) (ABIN7455106)
Target
Alle BMI1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 250-300
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Verwendungszweck
- Rabbit anti-BMI1 Recombinant Monoclonal Antibody [BLR119H]
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Immunogen
- between AA 250 and 300
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Andere Bezeichnung
- BMI1
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Hintergrund
- Background: BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
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Gen-ID
- 648
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NCBI Accession
- NP_005171
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UniProt
- P35226
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Pathways
- Zellzyklus, Autophagie
Target
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